Bacteriostatic effect of Sodium Lactate 50%. Sodium 2-hydroxyprop anoate. ), allergies, pre-existing diseases, and current health conditions (e.g. The contents of one container (50 mEq in 10 mL) added to 290 mL of a nonelectrolyte solution or of sterile water for injection will provide 300 mL of an approximately isotonic (1/6 molar) concentration of Sodium Lactate (1.9%), containing 167 mEq/liter each of Na+ and lactate anion. Sodium lactate is the sodium salt of lactic acid. Too rapid administration and overdosage should be avoided. ], Distributed by Hospira, INC., Lake Forest, IL 60045 USA. PROPANOIC ACID, 2-HYDROXY-,MONOSODIUM SALT Propanoic Acid, 2-Hydroxy-, Monosodium Salt. Medically reviewed by Drugs.com. chemBlink provides information about CAS # 72-17-3, Sodium lactate, Sodium DL-lactate, Lactic acid sodium salt, (+/-)-2-Hydroxypropionic acid sodium salt, molecular formula: C3H5NaO3. It is naturally produced in the skin, according to an article published in Cosmetics and Toiletries, and also occurs naturally in all animal and human muscle tissue, according to Sodium-Lactate.com. The potentially large loads of sodium given with lactate require that caution be exercised in patients with congestive heart failure or other edematous or sodium-retaining states, as well as in patients with oliguria or anuria. Sodium lactate 1/6 molar in plastic container . Page 1 of 6 Sodium Lactate 60% Solution CAS No 72-17-3 MATERIAL SAFETY DATA SHEET SDS/MSDS . Below are two batches of … The safety and effectiveness of Sodium Lactate have not been established in pediatric patients. Beilstein/REAXYS Number 4567087 . FOR INTRAVENOUS USE. Excessive administration of potassium-free solutions may result in significant hypokalemia. The amount of sodium ion and lactate ion to be added to larger volume intravenous fluids should be determined in accordance with the electrolyte requirements of each individual patient. Its limited use has been inadequate to fully define proper dosage and limitations for use. …sodium salt Formula: CH 3 CH(OH)COONa Formula Weight: 112.06 CAS No. Select one or more newsletters to continue. EC Number 212-762-3. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The solution contains no bacteriostat, antimicrobial agent or added buffer. Email: info@alfa-chemistry.com Tel:1-201-478-8534 1-516-662-5404 Fax: 1-516-927-0118 Address: 2200 Smithtown Avenue, Room 1 Ronkonkoma, NY 11779-7329 USA For product inquiries, please use our online system or send an email to inquiry@alfa-chemistry.com Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Sodium Lactate. Sodium Lactate has no advantage over sodium bicarbonate and may be detrimental in the management of lactic acidosis. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is a sterile, nonpyrogenic, concentrated solution of Sodium Lactate in water for injection. The recommended amount to use is about 1 … When oxidative activity is intact, one to two hours time is required for conversion of lactate to bicarbonate. Sodium Lactate Injection, USP 50 mEq must be suitably diluted before infusion to avoid a sudden increase in the level of sodium or lactate. Sodium Lactate Injection, USP 50 mEq is contraindicated in patients suffering from hypernatremia or fluid retention. The intravenous administration of this solution (after appropriate dilution) can cause fluid and/or solute overloading resulting in dilution of other serum electrolyte concentrations, overhydration, congested states or pulmonary edema. It is a free flowing hygroscopic salt and has a neutral pH.-Chemical name: Sodium lactate powder-Standard: Food grade FCC-Appearance: crystalline powder-Color: white color-Odor: odorless Sodium lactate hardens cold process soap so you can unmold and enjoy it more quickly. The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. The container requires no vapor barrier to maintain the proper drug concentration. ››Sodium Lactate molecular weight. Sodium ions are known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Synonym: (S)-2-Hydroxypropionic acid sodium salt, L-Lactic acid sodium salt, Sarcolactic acid sodium salt, Sodium L-lactate Empirical Formula (Hill Notation): C 3 H 5 NaO 3 Molecular Weight: 112.06 The safety of the plastic has been confirmed by tests in animals according to USP biological standards for plastic containers. Store at 20 to 25°C (68 to 77°F). Sodium Lactate 60% – Food Grade. In the event of overdosage, discontinue infusion containing Sodium Lactate immediately and institute corrective therapy as indicated to reduce elevated serum sodium levels and restore acid-base balance if necessary. Dist. Sodium Lactate SDS, Safety Data Sheet MSDS Sheet, Material Safety Data Sheet 05-Dec-20. Isotonic saline infusion can be used to expand the extracellular fluid volume, and it is also acidifying. Contains hydrochloric acid for pH adjustment. It's a liquid salt derived from the fermentation of sugars found in corn and beets. Discard unused portion. Sodium lactate and NH4Cl should not be administered to patients with liver disease. Adverse effects of Sodium Lactate are essentially limited to overdosage of either sodium or lactate ions. by Hospira, Inc., Lake Forest, IL 60045 USA, NDC 0409-6664-02 Lactate is one of the main components of Ringer′s lactate… Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is a sterile, nonpyrogenic, concentrated solution of Sodium Lactate in water for injection. Upon metabolism, sodium lactate is converted to bicarbonate, thereby increasing plasma bicarbonate, which facilitates removal of hydrogen ion and lactate … PubChem Substance ID 24896392. The sodium (Na+) ion combines with bicarbonate ion produced from carbon dioxide of the body and thus retains bicarbonate to combat metabolic acidosis (bicarbonate deficiency). Dosage Form: injection, solution, concentrate. Sodium Lactate. If you have an allergy to sodium lactate or any other part of sodium lactate. Jungbunzlauer sodium L (+)-lactate/sodium diacetate is a colourless to yellowish, syrupy liquid with a slight characteristic odour and a saline taste. Since metabolic conversion of lactate to bicarbonate is dependent on the integrity of cellular oxidative processes, lactate may be inadequate or ineffective as a source of bicarbonate in patients suffering from acidosis associated with shock or other disorders involving reduced perfusion of body tissues. Sodium Lactate is a sodium salt of racemic or inactive lactic acid with alkalinizing and electrolyte replenishing property. Significant hypokalemia may occur. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration. It's a natural ingredient approved by both ECOCERT and COSMOS. Before using Sodium Lactate, inform your doctor about your current list of medications, over the counter products (e.g. ).Some health conditions may make you more susceptible to the side-effects of the drug. Molecular Weight 112.06 . KCl is sometimes administered to alkalemic patients. The normal plasma level of lactate ranges from 0.9 to 1.9 mEq/liter. Sodium Lactate should be given to a pregnant woman only if clearly needed. Sodium lactate in plastic container . Molar mass of NaC3H5O3 = 112.05977 g/mol Convert grams Sodium Lactate to moles or moles Sodium Lactate to grams. Solutions containing sodium ions should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency and in clinical states in which there exists edema with sodium retention. The lactate anion is in equilibrium with pyruvate and has an alkalizing effect resulting from simultaneous removal by the liver of lactate and hydrogen ions. In the liver, lactate is metabolized to glycogen which is ultimately converted to carbon dioxide and water by oxidative metabolism. Sodium lactate is used in soap making to produce a harder long lasting bar of soap. Sodium lactate powder is the solid sodium salt of natural L-Lactic acid, Sodium lactate powder 98 is a white powder. Sodium is the principal cation of the extracellular fluid and plays a large part in fluid and electrolyte replacement therapies. It should not be administered undiluted. When diluted with water for injection to make a 1/6 molar solution, the pH of Sodium Lactate injection is 6.5 (6.0 to 7.3). Sodium lactate solution is a natural food additive, it is used as water retention agent, antioxidant synergists, emulsifiers, also can be used as pH adjusting agents (e.g. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL) is administered intravenously only after addition to a larger volume of fluid. You can also use it in lotion to draw moisture to the skin, or in hot process soap to make it more fluid and smooth. Empirical Formula (Hill Notation) C 3 H 5 NaO 3. Sodium Lactate Powder. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Demonstrates an anti-drying effect in various foods, particularly delicacies and confectioneries. MF: C3H5O3 Na, MW: 112.1 In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. Acetazolamide is a mild … CAUTION: MUST BE DILUTED. It comprises more than 90% of total cations at its normal plasma concentration of approximately 140 mEq/liter. It is seldom measured as such and thus is one of the "unmeasured anions" ("anion gap") in determinations of the ionic composition of plasma. Cautions. About Sodium Lactate Enquire Now. Molecular weight calculation: 22.98977 + 12.0107*3 + 1.00794*5 + 15.9994*3 The sodium ion exerts a primary role in controlling total body water and its distribution. Sodium L-lactate ~98% Synonym: (S)-2-Hydroxypropionic acid sodium salt, L-Lactic acid sodium salt, Sarcolactic acid sodium salt CAS Number 867-56-1. �A~�L>&G. It occurs naturally in the skin as part of the skin’s NMF (Natural Moisturizing Factors), and is an excellent humectant. See WARNINGS and PRECAUTIONS. For Intravenous Use. Sodium Lactate. CHF, shock, respiratory alkalosis or other conditions that increase lactate. Uses of Sodium Lactate: It is used to treat or prevent acid problems in the blood. Additive Number. 325. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. Sodium Lactate, a 60% concentration in water, and is the sodium salt of natural L(+)-Lactic Acid, produced through the fermentation of sugar, an alpha hydroxy acid that occurs everywhere in nature. Solutions containing lactate ions should be used with caution as excess administration may result in metabolic alkalosis. Caution must be exercised in the administration of parenteral fluids, especially those containing sodium ions, to patients receiving corticosteroids or corticotropin. Each 10 mL vial contains Sodium Lactate, anhydrous 5.6 g (50 mEq each of Na+ and lactate anion). Simply measure out the sodium lactate, and stir into the cool lye water. Excess administration may result in metabolic alkalosis �`z�O�ᄐ�/_�G!&���Z::��y np֬�9�Up���5�Ԝ���(e�H�x/.�l}���6���A�G8W4��_���X��s|���o�3�|��f�`@!P1��e�n�{�����6��_��r�/�����)��[�$�r%�1�\�7,�a�8A��*Ha5��!+��v����-X��t��"�6�U�\R��]�m��4L���SPg�A��a� �=7d ��x^�ɰ袯yN�;�p�� ��,� )o�����(��ȑx�y3�4����BϦE�i�46�qp0�>NyX_l|�)�k����.�ح�.�M�z9OS��| �؁x�� ����Lػ��6+�Wq��W�DKY��l Studies with Sodium Lactate Injection have not been performed to evaluate carcinogenic potential, mutagenic potential or effects on fertility. MDL number MFCD00066576. Our team of experts are at the ready. It should not be administered undiluted. Avoid rapid administration and overdosage. The semi-rigid vial is fabricated from a specially formulated polyolefin. It should not be used in conditions in which lactate levels are increased (e.g., shock, congestive heart failure, respiratory alkalosis) or in which utilization of lactate is diminished (e.g., anoxia, beriberi). Chemical Formula: C3H5NaO3 Molecular Weight: 112.06 CAS#: 867-56-1 (General: 72-17-3) Allergen Status: Product does not contain any of the known allergens including dairy, egg, wheat, soy, tree nuts, peanuts, fish and shellfish. CAS Number. Because many drugs are excreted in human milk, caution should be exercised when Sodium Lactate Injection is administered to a nursing mother. Sodium Lactate, USP is chemically designated CH3CH(OH)COONa, a 60% aqueous solution miscible in water. Contains 25 of NDC 0409-6664-11 Molecular Formula C 3 H 5 NaO 3; Average mass 112.060 Da; Monoisotopic mass 112.013641 Da; ChemSpider ID 6049 - Charge. Other Names. pregnancy, upcoming surgery, etc. Be careful not to use too much; using too much sodium lactate will result in a hard, crumbly bar of soap. Formula : C3H5NaO3 Molecular Weight : 112,06 g/mol No components need to be disclosed according to the applicable regulations. vitamins, herbal supplements, etc. Buy Sodium L-lactate (CAS 867-56-1), a simple 3 carbon sugar produced from pyruvate via LDH in mammals, from Santa Cruz. Other . You need this product in your collection. per pound of oils. This solution is stable under normal storage conditions. See WARNINGS and PRECAUTIONS. What do I need to tell my doctor BEFORE I take Sodium Lactate? This solution is stable under normal storage conditions, non-toxic to humans and the environment and readily biodegradable. Stars This entity has been manually annotated by the ChEBI Team. Sodium Lactate injection, solution, concentrate, We comply with the HONcode standard for trustworthy health information -, ANALYSIS(0409-6664), LABEL(0409-6664), MANUFACTURE(0409-6664), PACK(0409-6664). It is not intended nor effective for correcting severe acidotic states which require immediate restoration of plasma bicarbonate levels. The osmolar concentration is 10 mOsmol/mL (calc.). Lactate anion [CH3CH(OH)COO−] serves the important purpose of providing "raw material" for subsequent regeneration of bicarbonate (HCO3−) and thus acts as a source (alternate) of bicarbonate when normal production and utilization of lactic acid is not impaired as a result of disordered lactate metabolism. The sodium salt of lactic acid.It's a great skin moisturizer and also used to regulate the pH value of the cosmetic formula. An organic sodium salt having lactate as the counterion. China Sodium Lactate manufacturers - Select 2020 high quality Sodium Lactate products in best price from certified Chinese High Pressure Sodium manufacturers, Sodium Phosphate suppliers, wholesalers and factory on Made-in-China.com NOT FOR USE IN THE TREATMENT OF LACTIC ACIDOSIS. SMILES. Sodium Acetate Anhydrous is the anhydrous, sodium salt form of acetic acid.Sodium acetate anhydrous disassociates in water to form sodium ions (Na+) and acetate ions. An evaluation of current literature revealed no clinical experience identifying differences in response between elderly and younger patients. Sodium is the principal cation of extracellular fluid. It is a copolymer of ethylene and propylene. Sodium Lactate 50% demonstrates its water-retention effect even under conditions of low temperature and low humidity. Buy Sodium Lactate at BrambleBerry. Safety Data Sheets Download. Rx only. Other . More details: Systematic name. ... An organic sodium salt having lactate as … Sodium lactate (sodium lactate injection in aviva) is chemically designated as propanoic acid, 2-hydroxy-,monosodium salt and has the following structural formula: CH 3 CH (OH)COONa C 3 H 5 NaO 3 112.1 A 60% aqueous solution is miscible in water. Last updated on Dec 1, 2019. It is not known whether this drug is excreted in human milk. No advantage over sodium bicarbonate and is contraindicated in the treatment of lactic acidosis. The solution is administered after dilution by the intravenous route as an electrolyte replenisher and systemic alkalizer. Sodium Lactate is the natural salt derived from a natural fermentation product, lactic acid. It is derived from natural L(+) lactic acid, a weak acid having a dissociation 86 constant of 1.389.10-4 at 22°C (pKa=3.857).Sodium lactate has a content of 59-61% (w/w) and a Jungbunzlauer sodium L (+)-lactate is a colourless to yellowish, nearly odourless aqueous solution with a mild salty taste. All or part of the content(s) of one (50 mEq in 10 mL) or more vial containers may be added to other intravenous solutions to provide any desired number of milliequivalents of lactate anion (with the same number of milliequivalents of Na+). Do not administer unless solution is clear and seal is intact. The lactate in Compound Sodium Lactate solution is metabolized by both oxidation and gluconeogenesis, predominantly in the liver, and bicarbonate is generated by both processes over 1-2 h. When medication is added to Compound Sodium Lactate Solution, the overall pharmacokinetics of the solution will depend on the nature of the drug used. 72-17-3. 80 Sodium Lactate 81 The structural formula for sodium lactate is: 82 83 Figure 2: The structural formula of sodium lactate 84 85 Sodium lactate is hygroscopic. It is a significantly stronger humectant than vegetable glycerin, with over twice the water holding capability. SECTION 4: First aid … CAUTION: MUST BE DILUTED. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is primarily indicated, after dilution, as a source of bicarbonate for prevention or control of mild to moderate metabolic acidosis in patients with restricted oral intake whose oxidative processes are not seriously impaired. Lactate anion is usually present in extracellular fluid at a level of less than 1 mEq/liter, but may attain a level of 10 mEq/liter during exercise. Ultralac SL -60 (Sodium Lactate 60%) General Characteristics: Appearance: Clear, colorless liquid. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Molecular formula. In the soap making process, sodium lactate is added to the lye/water solution once the temperature is below 54 degrees Celsius. Specifications of Sodium Lactate Manufacturers. Sodium Lactate and Soap. Section 1: Chemical Product Identification If you are allergic to sodium lactate; any part of sodium lactate; or any other drugs, foods, or substances. Available for Android and iOS devices. Product Information. Sodium Lactate CAS Number 72-17-3 or 867-56-1, EINECS EC Number 200-772-0, HS Code ---**; Molecular Weight 112.06, Molecular Formula: C 3 H 5 NaO 3. [See USP Controlled Room Temperature. It is also not known whether Sodium Lactate can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. for the sake); seasoning materials; flavor modifiers; anti-cold agent; quality improver for baked … Animal reproduction studies have not been conducted with Sodium Lactate. In patients with diminished renal function, administration of solutions containing sodium ions may result in sodium retention. The usage rate for sodium lactate is 1 tsp. The solution is administered after dilution by the intravenous route as an electrolyte replenisher and systemic alkalizer. Sodium Lactate. 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